Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2018127
- Období řešení
- 1/2020 - 12/2022
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
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Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
- Spolupracující organizace
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Biotechnologický ústav AV ČR, v.v.i.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies, will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB is a part of the ESFRI project INSTRUCT-ERIC.
Cíle udržitelného rozvoje
Masarykova univerzita se hlásí k cílům udržitelného rozvoje OSN, jejichž záměrem je do roku 2030 zlepšit podmínky a kvalitu života na naší planetě.
Publikace
Počet publikací: 327
2022
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Methods for characterization of biomolecules at BIC Core facility, CEITEC MU
Rok: 2022, druh: Konferenční abstrakty
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Monofunctionalized Fluorinated Bambusurils and Their Conjugates for Anion Transport and Extraction
Journal of Organic Chemistry, rok: 2022, ročník: 87, vydání: 15, DOI
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Multiple approaches for protein phosphorylation: a story of 14-3-3
Rok: 2022, druh: Konferenční abstrakty
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NanoBiotech lab_BioAFM and MEA equipment I
Rok: 2022, druh: Popularizační texty
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NanoBiotech lab_BioAFM and MEA equipment II
Rok: 2022, druh: Popularizační texty
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NanoBiotech labs_Core facility presentation I
Rok: 2022, druh: Popularizační texty
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NanoBiotech labs_Core facility presentation II
Rok: 2022, druh: Popularizační texty
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Nanofibers of solid-solution thorium(IV)-uranium(IV) oxides by electrospinning
Journal of Nuclear Materials, rok: 2022, ročník: 566, vydání: August, DOI
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Non-aqueous synthesis of homogeneous molybdenum silicate microspheres and their application as heterogeneous catalysts in olefin epoxidation and selective aniline oxidation
Journal of Industrial and Engineering Chemistry, rok: 2022, ročník: 107, vydání: March, DOI
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Novel buffer screen for biomolecular characterization
Rok: 2022, druh: Konferenční abstrakty