Mathematical model of peripheral blood stem cell harvest kinetics
Autoři | |
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Rok publikování | 2003 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Bone Marrow Transplantation |
Fakulta / Pracoviště MU | |
Citace | |
www | http://www.nature.com/cgi-taf/DynaPage.taf?file=/bmt/journal/v32/n8/abs/1704226a.html |
Obor | Onkologie a hematologie |
Klíčová slova | mathematical model; cell separator; cell collection; peripheral blood stem cells; CD34+ cells; hematopoiesis |
Popis | A mathematical model of peripheral blood stem cell harvest was developped, taking two new parameters - number of recruited cells and efficiency of collection - into consideration in addition to concentration and collected ammount of cells. This model was tested on 241 harvest procedures in cancer patients, donors of allogenetic PBSC, and platelet donors, using different collection procedures, with Cobe Spectra Cell separator. |
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