Mathematical model of peripheral blood stem cell harvest kinetics

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Authors	MAYER Jiří POSPÍŠIL Zdeněk KOŘÍSTEK Zdeněk
Year of publication	2003
Type	Article in Periodical
Magazine / Source	Bone Marrow Transplantation
MU Faculty or unit	Faculty of Science
Citation
Web	http://www.nature.com/cgi-taf/DynaPage.taf?file=/bmt/journal/v32/n8/abs/1704226a.html
Field	Oncology and hematology
Keywords	mathematical model; cell separator; cell collection; peripheral blood stem cells; CD34+ cells; hematopoiesis
Description	A mathematical model of peripheral blood stem cell harvest was developped, taking two new parameters - number of recruited cells and efficiency of collection - into consideration in addition to concentration and collected ammount of cells. This model was tested on 241 harvest procedures in cancer patients, donors of allogenetic PBSC, and platelet donors, using different collection procedures, with Cobe Spectra Cell separator.
Related projects:	Functional-differential equations and mathematical-statistical models