Cystathionine β-synthase affects organization of cytoskeleton and modulates carcinogenesis in colorectal carcinoma cells

Varování

Publikace nespadá pod Fakultu sportovních studií, ale pod Lékařskou fakultu. Oficiální stránka publikace je na webu muni.cz.

Autoři	LISKOVA Veronika CHOVANCOVA Barbora BABULA Petr REZUCHOVA Ingeborg PAVLOV Kristina Ploth MATUSKOVA Miroslava KRIŽANOVÁ Oľga
Rok publikování	2023
Druh	Článek v odborném periodiku
Časopis / Zdroj	Frontiers in Oncology
Fakulta / Pracoviště MU	Lékařská fakulta
Citace
www	https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1178021/full
Doi	http://dx.doi.org/10.3389/fonc.2023.1178021
Klíčová slova	cystathionine beta-synthase; cytoskeleton; beta-tubulin; colorectal carcinoma cells; xenografts
Popis	Background: Cystathionine beta-synthase (CBS), one of three enzymes that endogenously produce hydrogen sulfide, is extensively studied for its relevance in the cells of various tumors. In our previous work, we observed that the immunofluorescence pattern of CBS is very similar to that of tubulin and actin. Therefore, we focused on the potential interaction of CBS with cytoskeletal proteins beta-actin and beta-tubulin and the functional relevance of the potential interaction of these proteins in colorectal carcinoma cell lines.