Visfatin and its role in obesity development

Varování

Publikace nespadá pod Fakultu sportovních studií, ale pod Lékařskou fakultu. Oficiální stránka publikace je na webu muni.cz.

Autoři	ŠŤASTNÝ Jiří BIENERTOVÁ VAŠKŮ Julie VAŠKŮ Anna
Rok publikování	2012
Druh	Článek v odborném periodiku
Časopis / Zdroj	Diabetes & Metabolic Syndrome: Clinical Research & Reviews
Fakulta / Pracoviště MU	Lékařská fakulta
Citace
Doi	http://dx.doi.org/10.1016/j.dsx.2012.08.011
Obor	Endokrinologie, diabetologie, metabolismus, výživa
Klíčová slova	Visfatin; NAMPT; Adipocytokines; Lipid metabolism; Obesity
Popis	Visfatin, a product of PBEF gene, is an adipocytokine that harbours strong insulin-mimetic activity and it has been reported previously to associate with obesity. Recent reports also provide evidence that Visfatin has also important intracellular effects as it is homologous with nicotinamide phosphoribosyltransferase (NAMPT). In this review, we summarize the main documented effects of Visfatin on metabolism in humans, with special emphasis put on the pathways associated with obesity.