Project information
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Project Identification
- LM2018127
- Project Period
- 1/2020 - 12/2022
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
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Central European Institute of Technology
- prof. RNDr. Vladimír Sklenář, DrSc.
- Cooperating Organization
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Institute of Biotechnology CAS
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies, will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB is a part of the ESFRI project INSTRUCT-ERIC.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 327
2022
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Methods for characterization of biomolecules at BIC Core facility, CEITEC MU
Year: 2022, type: Conference abstract
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Monofunctionalized Fluorinated Bambusurils and Their Conjugates for Anion Transport and Extraction
Journal of Organic Chemistry, year: 2022, volume: 87, edition: 15, DOI
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Multiple approaches for protein phosphorylation: a story of 14-3-3
Year: 2022, type: Conference abstract
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NanoBiotech lab_BioAFM and MEA equipment I
Year: 2022, type: Popularization text
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NanoBiotech lab_BioAFM and MEA equipment II
Year: 2022, type: Popularization text
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NanoBiotech labs_Core facility presentation I
Year: 2022, type: Popularization text
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NanoBiotech labs_Core facility presentation II
Year: 2022, type: Popularization text
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Nanofibers of solid-solution thorium(IV)-uranium(IV) oxides by electrospinning
Journal of Nuclear Materials, year: 2022, volume: 566, edition: August, DOI
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Non-aqueous synthesis of homogeneous molybdenum silicate microspheres and their application as heterogeneous catalysts in olefin epoxidation and selective aniline oxidation
Journal of Industrial and Engineering Chemistry, year: 2022, volume: 107, edition: March, DOI
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Novel buffer screen for biomolecular characterization
Year: 2022, type: Conference abstract