Project information
Determination of markers, screening and early diagnostics of cancer diseases using highly automated processing of multidimensional biomedical images
(Biomarker)
- Project Identification
- 2B06052
- Project Period
- 7/2006 - 6/2011
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Health and quality of life
- MU Faculty or unit
- Faculty of Informatics
- Keywords
- zpracování obrazu; optická mikroskopie; buněčné jádro; prostorové uspořádání; exprese genů; mikročipy; nádorová onemocnění; diagnostické markery
- Cooperating Organization
-
Brno University of Technology
- Responsible person doc. RNDr. Pavel Smrž, Ph.D.
- Responsible person Ing. Miloslav Richter, Ph.D.
The aim of the project is to develop new approaches to the processing of image data from fluorescence microscopy and microarrays that, in combination with the research in genomics and proteomics techniques, will help with the determination of markers, screening and early diagnostics of cancer diseases.
Results
Publications
Total number of publications: 121
2011
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On Euclidean Metric Approximation via Graph Cuts
Computer Vision, Imaging and Computer Graphics. Theory and Applications., year: 2011
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Proliferation and differentiation potential of CD133+ and CD34+ populations from the bone marrow and mobilized peripheral blood
Annals of hematology, year: 2011, volume: 90, edition: (2)
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Quantification of Golgi Complex Assembly and Disassembly in LiveCell Fluorescence Microscopy Images
Proceedings of Workshop on Microscopic Image Analysis with Applications in Biology, year: 2011
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Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment.
Cell Host & Microbe, year: 2011, volume: 9, edition: 1, DOI
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Simultaneous Tracking of Multiple Objects Using Fast Level Set-Like Algorithm
Sixth Doctoral Workshop on Mathematical and Engineering Methods in Computer Science (Selected Papers), year: 2011
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The MEK inhibitor PD184352 enhances BMS-214662-induced apoptosis in CD34+ CML stem/progenitor cells
Leukemia, year: 2011, volume: 25, edition: 7, DOI
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Tool for Generation of Synthetic Image Datasets for Time-Lapse Fluorescence Microscopy
Year: 2011, type: Conference abstract
2010
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A Fast Level Set-Like Algorithm for Region-Based Active Contours
6th International Symposium on Visual Computing, year: 2010
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A novel approach to evaluation of the spatial relationship of fluorescent signals in ImunnoFISH analysis of different kind.
Advances in Molecular and Cancer Biology, 2010, year: 2010
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A Simple Topology Preserving Max-Flow Algorithm for Graph Cut Based Image Segmentation
6th Doctoral Workshop on Mathematical and Engineering Methods in Computer Science, year: 2010