Project information
Determination of markers, screening and early diagnostics of cancer diseases using highly automated processing of multidimensional biomedical images
(Biomarker)
- Project Identification
- 2B06052
- Project Period
- 7/2006 - 6/2011
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Health and quality of life
- MU Faculty or unit
- Faculty of Informatics
- Keywords
- zpracování obrazu; optická mikroskopie; buněčné jádro; prostorové uspořádání; exprese genů; mikročipy; nádorová onemocnění; diagnostické markery
- Cooperating Organization
-
Brno University of Technology
- Responsible person doc. RNDr. Pavel Smrž, Ph.D.
- Responsible person Ing. Miloslav Richter, Ph.D.
The aim of the project is to develop new approaches to the processing of image data from fluorescence microscopy and microarrays that, in combination with the research in genomics and proteomics techniques, will help with the determination of markers, screening and early diagnostics of cancer diseases.
Results
Publications
Total number of publications: 121
2011
-
Endonuclease G interacts with histone H2B, AIF, and DNA topoisomerase II alpha during apoptosis as revealed by FRET analysis of living cells
Year: 2011, type: Conference abstract
-
Fast Anisotropic Filtering and Performance Evaluation Tool for Optical Flow in Biomedical Image Analysis
Year: 2011, type:
-
Fast Tracking Algorithm of GFP-Transfected Living Cells Based on the Chan-Vese Model
Year: 2011, type: Conference abstract
-
Generation of 3D Digital Phantoms of Colon Tissue
Proceedings of 8th International Conference on Image Analysis and Recognition, year: 2011
-
Human embryonic stem cells suffer from centrosomal amplification
Stem Cells, year: 2011, volume: 29, edition: 1, DOI
-
Image Division Technique in Pre-acquisition Analysis of Information Content for Automated Microscopy
Journal of Microscopy, year: 2011, volume: 242, edition: 3, DOI
-
Interaction of endonuclease G with histone H2B, AIF, and DNA topoisomerase II alpha during apoptosis as revealed by FRET imaging of living cells
Year: 2011, type: Conference abstract
-
Micro axial tomography: A miniaturized, versatile stage device to overcome resolution anisotropy in fluorescence light microscopy
Rev. Sci. Instrum., year: 2011, volume: 82, edition: 9
-
Multiple myeloma patients at peripheral blood stem cell harvest: restricted usage of TCR beta variable families
Clinical Immunology, year: 2011, volume: 138, edition: 1, DOI
-
Normalizing for Individual Cell Population Context in the Analysis of High-Content Cellular Screens
BMC Bioinformatics, year: 2011, volume: 12, edition: 485