Srovnání elektrické aktivity 2D a 3D modelů pacient-specifických kardiomyocytů diferencovaných z lidských indukovaných pluripotentních buněk

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Title in English Comparison of the electrical activity of 2D and 3D models of patient-specific cardiomyocytes differentiated from human induced pluripotent stem cells
Authors

ŠVECOVÁ Olga KRÁL Martin ZELENÁK Štefan PACHERNÍK Jiří BÁRTA Tomáš NOVOTNÝ Tomáš BÉBAROVÁ Markéta

Year of publication 2025
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description A lower value of short-term variability of the cycle length (STVCL) was observed in the 3D model (median 17.45 ms, Q1 7.68 ms, Q3 56.68 ms, vs. 31.5 ms, Q1 11.9 ms, Q3 100.5 ms) in the 2D model. Hence, the 3D model showed a better developed and more stable electrical activity, being a better model for the future functional analysis.
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