Bone marrow plasma cell separation - validation of separation algorithm
| Authors | |
|---|---|
| Year of publication | 2012 |
| Type | Article in Periodical |
| Magazine / Source | Clinical Chemistry and Laboratory medicine |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.1515/cclm-2012-8837 |
| Field | Oncology and hematology |
| Keywords | FACS; MACS; monoclonal gammopathy; multiple myeloma; plasma cell |
| Attached files | |
| Description | Monoclonal gammopathy is characterized by the presence of monoclonal immunoglobulin which is produced by a specifi c clone of terminally differentiated long-living plasma cells (PC) in the bone marrow. More detailed understanding of this clone at the genomic and proteomic level as well as its comparison with the population of normal PC is possible only after the clone is separated from other BM cells. |
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