Informace o projektu
Derivatization strategies revealing metabolic patterns in human pluripotent stem cells and progenitors by mass spectrometry
(Stem cells metabolites derivatization)
- Kód projektu
- MUNI/IGA/1208/2021
- Období řešení
- 1/2022 - 12/2022
- Investor / Programový rámec / typ projektu
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Masarykova univerzita
- Interní grantová agentura MU
- Fakulta / Pracoviště MU
- Přírodovědecká fakulta
Metabolites are intermediate or terminal products of cell biochemical pathways. Changes in metabolites reflect the state of cell physiology, including proliferation or differentiation. The proposed project will use one-step chemical derivatization for mass spectrometry detection of different metabolites to reveal metabolic states of pluripotent stem cells and derivatives in standard 2D (in solution derivatization) and advanced 3D cultures of stem cells and derivatives (on tissue derivatization).
Publikace
Počet publikací: 2
2022
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DERIVATIZATION STRATEGIES FOR SENSITIVE MONITORING OF SMALL MOLECULES ON TISSUE SAMPLES
Rok: 2022, druh: Konferenční abstrakty
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ONE STEP CHEMICAL DERIVATIZATION OF SECRETED CELL METABOLITES FOR SENSITIVE MASS SPECTROMETRY DETECTION
Rok: 2022, druh: Konferenční abstrakty