Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2018127
- Období řešení
- 1/2020 - 12/2022
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
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Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
- Spolupracující organizace
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Biotechnologický ústav AV ČR, v.v.i.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies, will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB is a part of the ESFRI project INSTRUCT-ERIC.
Cíle udržitelného rozvoje
Masarykova univerzita se hlásí k cílům udržitelného rozvoje OSN, jejichž záměrem je do roku 2030 zlepšit podmínky a kvalitu života na naší planetě.
Publikace
Počet publikací: 327
2021
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Cellular mechanosensing by means of atomic force microscopy
Rok: 2021, druh: Konferenční abstrakty
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CF Day
Rok: 2021, druh: Uspořádání konference
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c-kit2 G-quadruplex stabilized via a covalent probe: exploring G-quartet asymmetry
Nucleic Acids Research, rok: 2021, ročník: 49, vydání: 15, DOI
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c-kit2 G-Quadruplex Stabilized via a Covalent Probe: Exploring G-Quartet Asymmetry
Rok: 2021, druh: Konferenční abstrakty
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Classification of a Violacein-Producing Psychrophilic Group of Isolates Associated with Freshwater in Antarctica and Description of Rugamonas violacea sp. nov.
Microbiology Spectrum, rok: 2021, ročník: 9, vydání: 1, DOI
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Comparative analyses of angiosperm secretomes identify apoplastic pollen tube functions and novel secreted peptides
Plant Reproduction, rok: 2021, ročník: 34, vydání: 1, DOI
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Computational Enzyme Stabilization Can Affect Folding Energy Landscapes and Lead to Catalytically Enhanced Domain-Swapped Dimers
ACS Catalysis, rok: 2021, ročník: 11, vydání: 21, DOI
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COVALENTLY CROSS-LINKED HYALURONIC ACID/BSA/GELATINE HYDROGELS AS BETTER SURFACE FOR CELL CULTURE
CONFERENCE PROCEEDINGS - NANOCON 2020, rok: 2021
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Crucial factors governing the electrochemical impedance on protein-modified surfaces
Electrochimica Acta, rok: 2021, ročník: 388, vydání: AUG, DOI
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Crystal and Substituent Effects on Paramagnetic NMR Shifts in Transition-Metal Complexes
Inorganic Chemistry, rok: 2021, ročník: 60, vydání: 13, DOI