Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2015043
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
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Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec, Prague-West) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies (total investments will exceed 750 mil. CZK by the end of 2015), will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB as National Affiliated Center is a part of the ESFRI projects INSTRUCT.
Publikace
Počet publikací: 251
2019
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Nanoalloys – Influence of Precursors and Synthetic Parameters on Composition, Morphology, and Properties
Rok: 2019, druh: Konferenční abstrakty
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NanoTemper Technologies Symposium & Workshop
Rok: 2019, druh: Uspořádání workshopu
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Návštěva studentů Fakulty chemické VUT 2019
Rok: 2019, druh: Popularizační texty
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Návštěva studentů Přírodovědecké fakulty MU 2019
Rok: 2019, druh: Popularizační texty
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NMR and CryoEM excursion
Rok: 2019, druh: Popularizační texty
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Non-invasive electromechanical cell-based biosensors for improved investigation of 3D cardiac models
Biosensors & bioelectronics : the international journal for the professional involved with research, technology and applications of biosensors and related devices, rok: 2019, ročník: 124, vydání: JAN 15 2019, DOI
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Processing of proteomics data in KNIME
Rok: 2019, druh: Uspořádání workshopu
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Proteomics Identification and Validation of Desmocollin-1 and Catechol-O-Methyltransferase as Proteins Associated with Breast Cancer Cell Migration and Metastasis
Proteomics, rok: 2019, ročník: 19, vydání: 21-22, DOI
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Quantitative Biology of Human Shelterin and Telomerase: Searching for the Weakest Point
International Journal of Molecular Sciences, rok: 2019, ročník: 20, vydání: 13, DOI
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Selectively Oxidized Cellulose with Adjustable Molecular Weight for Controlled Release of Platinum Anticancer Drugs
Biomacromolecules, rok: 2019, ročník: 20, vydání: 4, DOI