MiR-34b is associated with clinical outcome in triple-negative breast cancer patients.

Varování

Publikace nespadá pod Fakultu sportovních studií, ale pod Lékařskou fakultu. Oficiální stránka publikace je na webu muni.cz.

Autoři	SVOBODA Marek ŠÁNA Jiří RÉDOVÁ Martina NAVRÁTIL Jiří PALÁCOVÁ Markéta FABIAN Pavel SLABÝ Ondřej VYZULA Rostislav
Rok publikování	2012
Druh	Článek v odborném periodiku
Časopis / Zdroj	Diagnostic Pathology
Fakulta / Pracoviště MU	Lékařská fakulta
Citace
www	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349474/?tool=pubmed
Doi	http://dx.doi.org/10.1186/1746-1596-7-31
Obor	Onkologie a hematologie
Klíčová slova	triple-negative breast cancer; miR-34a; miR-34b; miR-34c; prognosis
Popis	Breast cancer is the most common malignancy with the highest incidence rates among women worldwide. Triple-negative breast cancer (TNBC) represents the major phenotype of basal-like molecular subtype of breast cancer, characterized by higher incidence in young women and a very poor prognosis. MicroRNAs (miRNAs) are small non-coding RNAs playing significant role in the pathogenesis of many cancers including breast cancer. Therefore, miRNAs are also potential prognostic and/or predictive biomarkers in triple-negative breast cancer patients.