Effect of chronic fluoxetine treatment on methamphetamine i.v. self-administration in rats
Autoři | |
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Rok publikování | 2002 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Behavioural Pharmacology |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Farmakologie a lékárnická chemie |
Klíčová slova | fluoxetine; methamphetamine; "i.v. self-administration"; rats |
Popis | The present study was designed to investigate the influence of chronic treatment with fluoxetine on both the training and maintenance of i.v. methamphetamine self-administration. Our results indicate that 5-HT re-uptake inhibition by fluoxetine may suppress either reinforcing mechanisms or sensitization to methamphetamine eliciting drug-wanting behaviour. |
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