RBP-Tar – a searchable database for experimental RBP binding sites

• Autoři: GREŠOVÁ Katarína; RAČEK Tomáš; MARTINEK Vlastimil; ČECHÁK David; SVOBODOVÁ Radka; ALEXIOU Panagiotis
• Rok publikování: 2023
• Druh: Článek v odborném periodiku
• Časopis / Zdroj: F1000Research
• Fakulta / Pracoviště MU: Středoevropský technologický institut
• www: https://f1000research.com/articles/12-755/v2
• Doi: http://dx.doi.org/10.12688/f1000research.131014.2
• Klíčová slova: RNA Binding Proteins; CLIP; RBP; Web-server
• Popis: RNA-binding proteins (RBPs) play a critical role in regulating gene expression by binding to specific sites on RNA molecules. Identifying these binding sites is crucial for understanding the many functions of RBPs in cellular function, development and disease. Current experimental methods for identifying RBP binding sites, such as ultra-violet (UV) crosslinking and immunoprecipitation (CLIP), and especially the enhanced CLIP (eCLIP) protocol, were developed to identify authentic RBP binding sites experimentally.

Související projekty

• e-Infrastruktura CZ