Penis as a primary site of an extraskeletal Ewing sarcoma A case report
| Autoři | |
|---|---|
| Rok publikování | 2021 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Medicine |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | https://journals.lww.com/md-journal/Fulltext/2021/03190/Penis_as_a_primary_site_of_an_extraskeletal_Ewing.64.aspx |
| Doi | http://dx.doi.org/10.1097/MD.0000000000025074 |
| Klíčová slova | extraskeletal Ewing sarcoma; multidisciplinary treatment; penis |
| Popis | Rationale: The Ewing sarcoma family of malignant tumors is a group of tumors characterized by morphologically similar round-cell neoplasms and by the presence of a common chromosomal translocation; Ewing sarcoma family of tumors typically occur in children and young adults between 4 to 15 years of age. The primary tumor usually originates in the bone, extraskeletal localization is rare. Patient concern: We present a case report concerning a 32-year-old male patient with a primary involvement of the penis. Diagnosis: The histopathology from the first penile biopsy showed a small-cell neuroendocrine carcinoma; however, that result was based on a sample obtained at a different facility than the Sarcoma Center, where the investigating pathologist did not have the adequate expertise. The patient then underwent a radical penectomy and a second reading of the histology was demanded after a radical penile amputation when Ewing sarcoma with R1 resection was confirmed. Interventions: The patient was referred to the national Sarcoma Center, where - using a multidisciplinary approach - the treatment was started with curative intent. However, it was preceded by a non-standard initiation of the therapy due to the poor primary diagnosis. Outcomes: The non-standard therapy at the onset of the disease caused a poor prognosis of an otherwise curable diagnosis. Despite all that, the patient survived for a relatively long time. Lessons: The treatment of sarcomas with atypical localizations should be conducted by an experienced multidisciplinary team in a center with experience in sarcoma treatment. |
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