Human cardiac progenitor analysis in dystrophin cardiomyopathy after cardiac transplantation
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Rok publikování | 2018 |
Druh | Konferenční abstrakty |
Fakulta / Pracoviště MU | |
Citace | PEŠL, Martin, Šárka JELÍNKOVÁ, Guido CALUORI, Mária HOLICKÁ, Víta ŽAMPACHOVÁ, Petr NĚMEC, Petr DVOŘÁK a Vladimír ROTREKL. Human cardiac progenitor analysis in dystrophin cardiomyopathy after cardiac transplantation. In Cardiovascular Research. 2018. Dostupné z: https://dx.doi.org/10.1093/cvr/cvy060.101. |
Popis | We report for the first time human dystrophy (Becker type, BMD) cardiac progenitor analysis. Following rare cardiac transplantation in case of a symptomatic BMD samples were obtained and compared to healthy control samples. Heart failure is a frequent cause of death in muscle dystrophy patients. We hypothesized lower repair capacity of myocardium, possibly due to decreased percentage of reparative c-kit+ cells and their impaired migration capacity. |
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