Influence of titanium dioxide nanoparticles on 2,3,7,8-tetrachlorodibenzo-p-dioxin bioconcentration and toxicity in the marine fish European sea bass (Dicentrarchus labrax)

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Publikace nespadá pod Fakultu sportovních studií, ale pod Přírodovědeckou fakultu. Oficiální stránka publikace je na webu muni.cz.
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DELLA TORRE Camilla BUONOCORE Francesco FRENZILLI Giada CORSOLINI Simonetta BRUNELLI Andrea GUIDI Patrizia KOČAN Anton MARIOTTINI Michela MOTTOLA Filomena NIGRO Marco POZO Karla Andrea RANDELLI Elisa VANNUCCINI Maria Luisa PICCHIETTI Simona SANTONASTASO Marianna SCARCELLI Vittoria FOCARDI Silvano MARCOMINI Antonio ROCCO Lucia SCAPIGLIATI Giuseppe CORSI Ilaria

Rok publikování 2015
Druh Článek v odborném periodiku
Časopis / Zdroj Environmental Pollution
Fakulta / Pracoviště MU

Přírodovědecká fakulta

Citace
www http://www.sciencedirect.com/science/article/pii/S0269749114004254
Doi http://dx.doi.org/10.1016/j.envpol.2014.09.020
Obor Znečištění a kontrola vody
Klíčová slova Nano-TiO2 2 3 7 8-TCDD; CYP1A; Immunomodulation; Genotoxicity
Popis The present study investigated the influence of nano-TiO2 (1 mg L-1) on 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) (46 pg L-1) bioconcentration and toxicity in the European sea bass (Dicentrarchus labrax) during 7 days in vivo exposure. A multimarkers approach was applied in different organs: detoxification in liver; innate immunity and pro-inflammatory response and adaptive immunity in gills and spleen; genotoxicity in peripheral erythrocytes and muscle. Bioconcentration of 2,3,7,8-TCDD in presence of nano-TiO2 was investigated in liver, skin and muscle as well as interaction between nanoTiO(2) and organic pollutants in artificial sea water (ASW). Nano-TiO2 negatively influenced immune response induced by 2,3,7,8-TCDD in spleen but not in gills and reduced the DNA damage induced by 2,3,7,8-TCDD in erythrocytes. nano-TiO2 did not interfere with 2,3,7,8-TCDD detoxification and bioconcentration according to the observed no interaction of the nano-TiO2 with organic pollutants in ASW.
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