Doxorubicin and liposomal doxorubicin affect microRNA expression in rat right ventricles
| Autoři | |
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| Rok publikování | 2014 |
| Druh | Konferenční abstrakty |
| Citace | NOVÁK, Jan; Tibor STRAČINA a Marie NOVÁKOVÁ. Doxorubicin and liposomal doxorubicin affect microRNA expression in rat right ventricles. In New Frontiers in Basic Cardiovascular Research 2014. 2014. ISBN 978-80-8141-064-2. |
| Popis | In order to better understand the acute effects of doxorubicin (DOX) and liposomal DOX on the heart, analysis of 4 selected microRNAs (miR-208a/146a/216b/let-7g) that may be involved in DOX-induced cardiotoxicity was performed, both in the left and right ventricles of the Wistar rat exposed to one dose of DOX/liposomal DOX. This acute administration of mentioned drugs affects stightly expression of selected microRNAs, especially in right ventricle. |
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