Uric acid, allopurinol therapy, and mortality in patients with acute heart failure — results of the Acute HEart FAilure Database registry

• Autoři: MÁLEK Filip; OŠŤÁDAL Petr; PAŘENICA Jiří; JARKOVSKÝ Jiří; VÍTOVEC Jiří; WIDIMSKÝ Petr; LINHART Aleš; FEDORCO Marián; COUFAL Zdeněk; MIKLÍK Roman; KRŰGER Andreas; VONDRAKOVÁ Dagmar; ŠPINAR Jindřich
• Rok publikování: 2012
• Druh: Článek v odborném periodiku
• Časopis / Zdroj: Journal of Critical Care
• Fakulta / Pracoviště MU: Lékařská fakulta
• Doi: http://dx.doi.org/10.1016/j.jcrc.2012.03.011
• Obor: Kardiovaskulární nemoci včetně kardiochirurgie
• Klíčová slova: Uric acid; Acute heart failure; Allopurinol; Mortality
• Popis: Study Objective: The aim of this study was to explore the prognostic role of serum uric acid (UA) measurement in the hospital and long-term mortality assessment in subjects with acute heart failure (AHF) from the Acute HEart FAilure Database registry (AHEAD). The AHEAD registry comprised 4153 patients with AHF syndromes hospitalized at the AHEAD participating centers. Patients and Methods: The study included 1255 patients who were admitted to the AHEAD participating centers with acute decompensated chronic heart failure, de novo heart failure, or cardiogenic shock between September 2006 and October 2009 and who had information about serum UA concentration available at the time of hospital admission. The hospital and long-term mortality was followed using the centralized database of the Ministry of Health, Czech Republic.

Související projekty

• Komplexní managenent péče o pacienty s akutním srdečním selháním, jejich střednědobá prognóza a multivariantní prognostický model