Major clonal lineages in impetigo Staphylococcus aureus strains isolated in Czech and Slovak maternity hospitals
| Název česky | Nejvýznamnější klonální linie u kmenů Staphylococcus aureus způsobujících impetigo v českých a slovenských porodnicích |
|---|---|
| Autoři | |
| Rok publikování | 2012 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | International Journal of Medical Microbiology |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | http://www.sciencedirect.com/science/article/pii/S1438422112000173 |
| Doi | http://dx.doi.org/10.1016/j.ijmm.2012.04.001 |
| Obor | Genetika a molekulární biologie |
| Klíčová slova | Staphylococcal skin infections; Exfoliative toxins; Multilocus sequence typing; DNA typing; Lysogeny |
| Přiložené soubory | |
| Popis | One hundred and twenty-seven exfoliative toxin-producing (ET-positive) strains of Staphylococcus aureus collected in 23 Czech and one Slovak maternity hospitals between 1998 and 2011 were genotypically characterized by multilocus sequence typing (MLST), pulsed-field gel electrophoresis (PFGE) profiling, spa gene polymorphism analysis, and ETA-converting prophage carriage, which resulted in the identification of 21 genotypes grouped into four clonal complexes (CC). Ninety-one isolates carried the eta gene alone while 12 isolates only harboured the etb gene. Two new, to date not defined, spa types (t6644 and t6645) and two novel sequence types (ST2194 and ST2195) were identified in the set of strains under study. The predominant CC121 occurred in 13 Czech hospitals. CC15, CC9, and ST88 (CC88) exclusively included eta gene-positive strains while the strains belonging to ST121 harboured the eta and/or etb genes. This study highlights not only significant genomic diversity among impetigo strains and the distribution of major genotypes disseminated in the Czech and Slovak maternity hospitals but also reveals their impact in epidermolytic infections. |
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