Project information
MEDGENET - Medical genomics and epigenomics network
(MEDGENET)
- Project Identification
- 692298
- Project Period
- 1/2016 - 12/2018
- Investor / Pogramme / Project type
-
European Union
- Horizon 2020
- Spreading excellence and widening participation
- MU Faculty or unit
- Central European Institute of Technology
- Cooperating Organization
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European Molecular Biology Laboratory
Uppsala universitet
Centre for Research and Technology Hellas
The main goal of MEDGENET consortium is to use synergies and existing expertise in EU leading institutions such as EMBL, Uppsala University and CERTH to reinforce the productivity and competitiveness of the CEITEC in the field of medical genomics and epigenomics. We propose clear strategy based on combination of unique complementary skills present in partner institutions that will transform CEITEC into a key leader in the field. ERA Chair who recently joint CEITEC already initiated the transformational change of the institute and TWINNING framework will further support sharing her international contacts with other CEITEC researchers. MEDGENET aims to create well-educated taskforce of biomedical researchers, who will notably contribute to the development of new genomics and bioinformatics tools and their application in clinical practice. Proposed project will enable to establish the best practices for performing innovative and high-quality biomedical research and to strengthen CEITEC´s competence to translate the research results into high value-added clinical applications. Stimulation of knowledge exchange, implementation of cutting edge technologies and mastery of modern genomics and bioinformatics methodologies will have a direct impact on the overall research and innovation potential of CEITEC and will increase its visibility in the international scientific community.
Publications
Total number of publications: 52
2018
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Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia
BMC Bioinformatics, year: 2018, volume: 19, edition: NOV, DOI
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CD20 is a direct regulator of B-cell receptor signaling in the microenvironment of chronic lymphocytic leukemia
Year: 2018, type: Conference abstract
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CD20 supports BCR signaling in an intra clonal aggressive chronic lymphocytic leukemia subpopulation of cells and rituximab primarily targets these BCR proficient B cells in vivo
Year: 2018, type: Conference abstract
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Dynamics of microRNA expression during early onset epileptogenesis
Year: 2018, type: Conference abstract
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ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-update on methodological approaches and results interpretation
Leukemia, year: 2018, volume: 32, edition: 5, DOI
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Evolution of genomic abnormalities during CLL disease course is associated with telomere length changes
Year: 2018, type: Conference abstract
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Gene aberrations in adult patients with Ph-negative ALL in the Czech Republic
Year: 2018, type: Conference abstract
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Multiple productive IGH rearrangements denote oligoclonality even in immunophenotypically monoclonal CLL
Leukemia, year: 2018, volume: 32, edition: 1, DOI
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MYC-mediated downregulation of miR-150 contributes to the transformation of follicular lymphoma by upregulating FOXP1 levels
Year: 2018, type: Conference abstract
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MYC-mediated downregulation of miR-150 contributes to the transformation of follicular lymphoma to DLBCL by upregulating FOXP1 levels
Year: 2018, type: Conference abstract