Project information
Plasticity of Regulatory Mechanisms of the Central Nervous Systems
- Project Identification
- MSM141100001
- Project Period
- 1/1999 - 1/2004
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Faculty of Medicine
- Keywords
- Plasticity; Regulatory Mechanisms; Central Nervous System; Preclinical and Clinical Aspects; Neurobiology; Neurophysiology; Neuroanatomy; Neuropharmacology; Clinical Neurology; Psychiatry; Regeneration Processes; Neurotransmitters; Epilepsy
The central nervous system, its neurobiological mechanisms and the possibilities of influencing them externally have become the subject of the BRAIN DECADE in the research strategy announced by president Bush and enacted in the USA in 1990, to which Europe joined in 1992. The intentions included into the project being submitted, i.e. the investigation of the neurobiological and neurophysiological mechanisms of the control of the motor and mental functions, of their abnormalities, and the possible therapeutic or preventive influencing of these are completely in line with the "Brain Decade" programme. The project a based on an integration of the of pre-clinical aspects of the research in neuroanatomy, neurophysiology, pharmacology, and clinical research in the clinical fields of neurology, neurosurgery, plastic surgery and psychiatry. 16 postgraduate students have been included into this faculty research.
Publications
Total number of publications: 705
1999
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Immunohistochemical localization of some extracellular molecules and their integrin receptors in the rat Pacinian corpuscles
General Physiology and Biophysics, year: 1999, volume: 18, edition: 1
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In vivo Migration of Schwann Cells in Absence of the Basal Lamina
Scripta Medica, year: 1999, volume: 72, edition: 5-6
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Influence of immunomodulation on CYP2D activity in rats.
Homeostasis, year: 1999, volume: 39, edition: 3-4
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Influence of pretreatment with immunosuppressants on O-demethylation of dextromethorphan in isolated perfused rat liver
Experimental and Toxicologic Pathology, year: 1999, volume: roč. 51, edition: 4-5
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Migration of Schwann cells and regeneration of peripheral nerves
E. J. Pathol. Histol., year: 1999, volume: 5, edition: 2
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Minimální diagnostický a terapeutický standard u pacientů s epilepsii.
Year: 1999, edition: Vyd. 1., number of pages: 8 s.
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Model "i. v. drug self-administration" u potkanů jako metoda studia farmakologických mechanismů podílejících se na matamfetaminové závislosti
Československá fyziologie, year: 1999, volume: 48, edition: 4
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Moderní antidepresíva
Nové poznatky o terapii starších nemocných, year: 1999
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Modulation of morphine behavioral effects by fluoxetine
Abstracts, 17th Anniversary - 61st Annual Scientific Meeeting, College on Problems of Drug Dependence, year: 1999
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Ovlivnění průběhu N-acetylace prokainamidu imunosupresivy v izolovaných játrech potkana.
Česká fyziologie, year: 1999, volume: 48, edition: 4