Determination of amino acids by capillary electrophoresis using reversed electro-osmotic flow: a critical evaluation

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Authors	MÁDR Aleš SVOBODOVÁ Kateřina GLATZ Zdeněk
Year of publication	2012
Type	Conference abstract
MU Faculty or unit	Faculty of Science
Citation
Description	Capillary electrophoresis with contactless conductivity detection (CCD) is useful combination for an analysis of the polar compounds with no chromophores in the structure. Using conventional UV/Vis spectrophotometric detection, derivatization of the analytes is needed. When CCD is used, derivatization of a sample can be omitted. However, it is a little bit challenging to keep a signal-to-noise ratio in a suitable range for the analytical purposes, when complex buffers are employed. The case is subject of this contribution.
Related projects:	Capillary electrophoresis as a member of the metabolomic analytical toolbox