MiR-195, miR-196b, miR-181c, miR-21 expression levels and MGMT methylation status are associated with clinical outcome in glioblastoma patients.
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| Year of publication | 2011 |
| Type | Conference abstract |
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| Description | Glioblastoma multiforme (GBM) is the most frequently occuring primary malignant brain tumor with very poor prognosis and different response to treatment. Therefore, it is very important to find new biomarkers which can predict a clinical outcomes and help in treatment decisions. MicroRNAs are small, non-coding RNAs that function as post-transcriptional regualtors of ene expression and play key role in pathogenesis of GBM. |