ZPŮSOB DETOXIKACE SULFIDICKÉHO YPERITU ÚČINKEM HALOGENALKANDEHALOGENÁZ

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Title in English Method of Detoxification of Yperite by using Haloalkane Dehalogenases
Authors

PROKOP Zbyněk DAMBORSKÝ Jiří OPLUŠTIL František FOŘTOVÁ Andrea NAGATA Yuji

Year of publication 2007
Type Patent
MU Faculty or unit

Faculty of Science

Publisher Úřad průmyslového vlastnictví ČR
State Czech Republic
Patent's number 298287
Description The method of detoxification of yperite by the use of haloalkane dehalogenases or their compositions, the method of preparation of dehalogenationating enzymes and of decontamination compositions which contain at least one wild type and/or modified haloalkane dehalogenase (EC 3.8.1.5) as an chemically active component. The preferred dehalogenases are DhaA from Rhodococcus rhodochrous NCIMB 13064, DmbA from Mycobacterium bovis 5033/66 or LinB from Sphingomonas paucimobilis UT26. Decontamination is utilized for detoxification of yperite from the surfaces of instrumentality, constructional objects, the people’s or animal’s skin and elements of environment, when yperite is exposed to the action of decontamination composition at +10 C to +70 C, preferably at +40C and pH = 4 to 12.
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