Embryonální test s Danio rerio pro výzkum endokrinní disrupce ve vodním prostředí.

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Title in English	DANIO RERIO EMBRYO TEST FOR RESEARCH OF ENDOCRINE DISRUPTION IN WATER ENVIRONMENT
Authors	JONÁŠ Adam JAROŠOVÁ Barbora SOVADINOVÁ Iva BLÁHA Luděk
Year of publication	2011
Type	Article in Periodical
Magazine / Source	Bulletin VÚHR Vodňany
MU Faculty or unit	Faculty of Science
Citation
Field	Environment influence on health
Keywords	Danio rerio; in vitro reporter gene test for estrogenicity; RT-PCR; waste water treatment works.
Description	This embryo test finds broad application. In the present study, we have investigated effects of waste water treatment plants originating from the Czech Republic on D. rerio embryos in the acute test. Further, we discuss possible extension of the current assay by investigating other highly sensitive parameters of chronic toxicity such as expression of specific genes including aromatase B, vitellogenin 1, estrogen receptor alpha and beta-actin.
Related projects:	Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL) Centrum pro výzkum toxických látek v prostředí