Does repetitive transcranial magnetic stimulation have a positive effect on working memory and neuronal activation in treatment of negative symptoms of schizophrenia?

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Authors

PŘIKRYL Radovan MIKL Michal PŘIKRYLOVÁ KUČEROVÁ Hana USTOHAL Libor KAŠPÁREK Tomáš MAREČEK Radek VRZALOVÁ Michaela ČEŠKOVÁ Eva VANÍČEK Jiří

Year of publication 2012
Type Article in Periodical
Magazine / Source Neuroendocrinology Letters
MU Faculty or unit

Central European Institute of Technology

Citation
Web http://www.ncbi.nlm.nih.gov/pubmed/22467118
Field Psychiatry, sexuology
Keywords cognitive functions; fMRI; neuronal activation; negative symptoms;
Attached files
Description Stimulation treatment led to a reduction of seriousness of negative schizophrenia symptoms in both comparative groups. However, mutual comparison of real (n=19) and sham (n=11) rTMS, respectively, has shown that the effect of real rTMS was statistically significantly higher compared with placebo stimulation. During stimulation treatment an improvement in working memory performance was also found. No statistically significant difference between the real and placebo sham rTMS, respectively, was established. The rate of neuronal activation did not change at all during rTMS treatment.
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