Způsob detekce chromozomální translokace t(11;14)(q13;q32) a oligonukleotidy pro použití při tomto způsobu

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Title in English	Method of detection of chromosomal translocation t (11; 14) (q13; Q32) and oligonucleotides for use in this way
Authors	TICHÝ Boris ŠUPÍKOVÁ Jana POSPÍŠILOVÁ Šárka MAYER Jiří
Year of publication	2011
Type	Patent
MU Faculty or unit	Faculty of Medicine
Publisher	Úřad průmyslového vlastnictví
State	Czech Republic
Patent's number	302581
Description	Method of detection of chromosomal translocation t (11; 14) (q13; Q32) lies in the fact that the DNA obtained from samples of biological material detects the presence of translocation t (11; 14) (q13; Q32) using long-range multiplex PCR (multiplex long -range PCR) using sets of primers covering regions on chromosomes 11 and 14, which usually result in the breakage. The method allows the detection in most samples, in which translocation is present and allows rapid characterization of site-specific design fault detection kits for monitoring minimal residual disease.
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