Clinicopathological correlations of nestin expression in surgically resectable pancreatic cancer including an analysis of perineural invasion
| Authors | |
|---|---|
| Year of publication | 2011 |
| Type | Article in Periodical |
| Magazine / Source | Journal of Gastrointestinal and Liver Diseases |
| MU Faculty or unit | |
| Citation | |
| Field | Other medical specializations |
| Keywords | Pancreatic cancer; nestin; prognostic factor; perineural invasion. |
| Description | An intimate link of nestin to biological process of pancreatic cancer was confirmated. The expression of nestin did not prove to be valuable prognostic factor and an immunohistochemical assesment of nestin expression is not superior to conventional prognostic factors in PDAC. A correlation between nestin expression in tumor cells and PNI was not confirmed and expression of nestin in nerve fibres of both PDAC and CP tissues seems to reflect the process of neural remodeling responsible for pancreatic neuropathy. |
| Related projects: |