Nejvýznamnější lékové interakce antipsychotik v průběhu života

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Title in English	Significant drug interactions of antipsychotics during the age
Authors	PŘIKRYL Radovan
Year of publication	2012
Type	Article in Periodical
Magazine / Source	Postgraduální medicina
MU Faculty or unit	Faculty of Medicine
Citation
Field	Psychiatry, sexuology
Keywords	antipsychotic; CYP450; pharmacodynamics; pharmacokinetics; interactions
Attached files	Interakce_antipsychotik_postgradualni_medicina_2011.pdf
Description	Drug interaction is a phenomenon, when the effects of the parent drug is changed, because adding a drug to cure other deficiencies will be combined with certain types of food. The importance of drug interactions increases with polypharmacy. Interactions occur at the level of antipsychotics pharmacodynamic and pharmacokinetic. Basic knowledge of psychiatrists should be aware of the receptor profile and the main routes of metabolism of psychotropic drugs.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.