A new quantitative description of intracellular Ca2+ dynamics in the model of rat ventricular myocyte

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Authors	PÁSEK Michal ŠIMURDA Jiří
Year of publication	2011
Type	Article in Proceedings
Conference	Engineering Mechanics 2011
MU Faculty or unit	Faculty of Medicine
Citation
Field	Biophysics
Keywords	cardiac cell; ICa; mathematical model
Attached files	EM2011_Pasek_Simurda.pdf
Description	The paper presents a new description of intracellular Ca2+ dynamics in the model of rat ventricular myocyte. The principal modifications based on the recently published data comprise: formulation of the function of peripheral dyads, incorporation of peripheral and tubular intracellular subspaces, reformulation of inactivation properties of surface of tubular ICa and description of the function of exogenous Ca2+ buffer in the intracellular space.
Related projects:	Early diagnostics and treatment of cardiovascular diseases