Interleukin-1 gene variations in post-orthodontic external root resorption

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Authors	LINHARTOVÁ Petra ČERNOCHOVÁ Pavlína RAUDENSKÁ Martina LIPKOVÁ Jolana IZAKOVIČOVÁ HOLLÁ Lydie
Year of publication	2011
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	External apical root resorption (EARR) is a permanent shortening of the end of the tooth root. EARR is a common clinical complication of orthodontic treatment and is known to occur after trauma and in response to inflammation. Polymorphisms in the interleukin-1 (IL-1) genes play a role in the inflammatory diseases through the modulation of cytokine levels. The aim of this study was to associate two single nucleotide polymorphisms (SNPs) and one variable number of tandem repeats (VNTR) polymorphism in IL-1 with EARR in the Czech population. This study was supported by projects 1M0528 and IGA NT11405-6.
Related projects:	Dental research centre Mikrobiologické a genetické determinanty rozvoje a progrese parodontitidy u diabetiků 1. a 2. typu a jejich reciproční vztah ke kompenzaci diabetu