On Parameter Synthesis by Parallel Model Checking
Authors | |
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Year of publication | 2012 |
Type | Article in Periodical |
Magazine / Source | IEEE/ACM Transactions on Computational Biology and Bioinformatics |
MU Faculty or unit | |
Citation | BARNAT, Jiří, Luboš BRIM, Adam KREJČÍ, Adam STRECK, David ŠAFRÁNEK, Martin VEJNÁR and Tomáš VEJPUSTEK. On Parameter Synthesis by Parallel Model Checking. IEEE/ACM Transactions on Computational Biology and Bioinformatics. Los Alamitos: IEEE Computer Society, 2012, vol. 9, No 3, p. 693-705. ISSN 1545-5963. Available from: https://dx.doi.org/10.1109/TCBB.2011.110. |
web | http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=5963639 |
Doi | http://dx.doi.org/10.1109/TCBB.2011.110 |
Field | Informatics |
Keywords | biological networks; parallel model checking; dynamical systems; parameter synthesis; systems biology |
Description | An important problem in current computational systems biology is to analyse models of biological systems dynamics under parameter uncertainty. This paper presents a novel algorithm for parameter synthesis based on parallel model checking. The algorithm is conceptually universal with respect to the modelling approach employed. We introduce the algorithm, show its scalability, and examine its applicability on several biological models. |
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