1,3-Dipolar cycloadditions of new functionalized cyclic nitrones

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Authors

HEBANOVÁ Simona BUCHLOVIČ Marian POTÁČEK Milan

Year of publication 2011
Type Conference abstract
MU Faculty or unit

Faculty of Science

Citation
Description We have studied the chemistry of new 5-membered cyclic nitrones bearing different functional groups in positions 2 and 5 of the nitrone ring. Nitrones were treated with various dipolarophiles. Reactions offered isoxazoles as single diastereomers in all studied cases. The reaction scope and limitations of studied 1,3-DC are presented. Substituent effect of nitrones and effect of dipolarophile reactivity upon reaction conversions and reaction yields is discussed.
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