Non-Invasive Assessment of Embryo Viability In Assisted Reproduction using Capillary Electrophoresis

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Authors

MÁDR Aleš FOLTOVÁ Kateřina ŽÁKOVÁ Jana LOUSOVÁ Eva CRHA Igor GLATZ Zdeněk

Year of publication 2011
Type Conference abstract
MU Faculty or unit

Faculty of Science

Citation
Description Multiple gestations are the one of the main problems associated with human assisted conception which originate from higher number of embryos implanted to increase the chance of successful implantation. More than four decades ago there were gradually revealed correlations between glucose, lactate, pyruvate and amino acids uptake and embryo viability. There were published many articles which offering different analytical tools to measure carboxylic and amino acids concentration thus provide addition information for selection of the most suitable embryos for implantation, namely LC and GC coupled with MS or MS/MS, 1H-NMR, Raman and near-infrared spectroscopy. Suitability of capillary electrophoresis for non-invasive assessment of embryo viability is presented.
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