Association of eNOS gene polymorphisms T-786C and G894T with blood pressure variability in man

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Authors	JÍRA Miroslav ZÁVODNÁ Eva HONZÍKOVÁ Nataša NOVÁKOVÁ Zuzana VAŠKŮ Anna IZAKOVIČOVÁ HOLLÁ Lydie FIŠER Bohumil
Year of publication	2011
Type	Article in Periodical
Magazine / Source	Physiological Research
MU Faculty or unit	Faculty of Medicine
Citation
Web	http://www.biomed.cas.cz/physiolres/pdf/60/60_193.pdf
Field	Physiology
Keywords	Arterial blood pressure variability; Spectral analysis; Nitric oxide synthase; Genetics; Polymorphism
Description	The aim of this study was to evaluate the association of polymorphisms T-786C and G894T in the gene encoding eNOS with blood pressure variability (BPV) in man. In conclusion, the haplotype formed by less frequent alleles of both eNOS variants was associated with increased systolic and diastolic BPV in this study.
Related projects:	Early diagnostics and treatment of cardiovascular diseases