The atherogenic index of plasma is increased by hormonal contraception

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Authors	SOŠKA Vladimír FIALA Jindřich NEBESKÁ Kateřina JARKOVSKÝ Jiří HRUBÁ Drahoslava
Year of publication	2011
Type	Article in Periodical
Magazine / Source	SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
MU Faculty or unit	Faculty of Medicine
Citation
Doi	http://dx.doi.org/10.3109/00365513.2011.553240
Field	Cardiovascular diseases incl. cardiosurgery
Keywords	Oral contraceptives; dyslipidemias; cardiovascular diseases; risk factors; HDL cholesterol; triglycerides; C-reactive protein
Description	The aim of this study was to determine if hormonal contraceptives affect the new atherogenic index of plasma (AIP) = log[triglycerides (TG)/high-density lipoprotein cholesterol (HDL-C)] together with the total cholesterol/HDL-C (TC/HDL-C) and the apolipoprotein B/apolipoprotein A1 (apoB/apoA1) ratios. The increased AIP and hs-CRP concentration after 9 months of hormonal contraception demonstrate that contraceptive-induced dyslipidemia has a proatherogenic nature, even when the TC/HDL-C and the apoB/apoA1 ratios are unchanged.
Related projects:	Hodnocení účinků různých typů hormonálních kontraceptiv na biochemické ukazatele kardiovaskulárního rizika žen s rozdílným kuřáckým a výživovým chováním a možnosti jejich ovlivnění