Serum metallothionein in newly diagnosed patients with childhood solid tumours

• Authors: KŘÍŽKOVÁ Soňa; MASAŘÍK Michal; MAJZLÍK Petr; KUKAČKA Jiří; KRUSEOVÁ Jarmila; ADAM Vojtěch; PRŮŠA Richard; ECKSCHLAGER Tomáš; STIBOROVÁ Marie; KIZEK René
• Year of publication: 2010
• Type: Article in Periodical
• Magazine / Source: Acta Biochimica Polonica
• MU Faculty or unit: Faculty of Medicine
• Field: Biochemistry
• Keywords: metallothionein; cancer; serum; Brdicka reaction; marker
• Description: Tumour markers are substances produced by malignant cells or by the organism as a response to cancer development. Determination of their levels can, therefore, be used to monitor the risk, presence and prognosis of a cancer disease or to monitor the therapeutic response or early detection of residual disease.Results found in this work indicate that the MT level in blood serum can be considered as a promising marker for diagnostics, prognosis and estimation of therapy efficiency of childhood tumours.

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