Serum metallothionein in newly diagnosed patients with childhood solid tumours

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Authors

KŘÍŽKOVÁ Soňa MASAŘÍK Michal MAJZLÍK Petr KUKAČKA Jiří KRUSEOVÁ Jarmila ADAM Vojtěch PRŮŠA Richard ECKSCHLAGER Tomáš STIBOROVÁ Marie KIZEK René

Year of publication 2010
Type Article in Periodical
Magazine / Source Acta Biochimica Polonica
MU Faculty or unit

Faculty of Medicine

Citation
Field Biochemistry
Keywords metallothionein; cancer; serum; Brdicka reaction; marker
Description Tumour markers are substances produced by malignant cells or by the organism as a response to cancer development. Determination of their levels can, therefore, be used to monitor the risk, presence and prognosis of a cancer disease or to monitor the therapeutic response or early detection of residual disease.Results found in this work indicate that the MT level in blood serum can be considered as a promising marker for diagnostics, prognosis and estimation of therapy efficiency of childhood tumours.
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