Současný pohled na indikace podání kombinace inhibitorů ACE a sartanů

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Title in English	Current perspective on indications for administering the combination of ACEI and sartans
Authors	VÍTOVEC Jiří ŠPINAR Jindřich
Year of publication	2010
Type	Article in Periodical
Magazine / Source	Interní medicína pro praxi
MU Faculty or unit	Faculty of Medicine
Citation
Field	Other specializations of internal medicine
Keywords	angiotenzin-converting enzyme inhibitors; angiotenzin II type 1 receptor blockers (sartans); hypertension; heart failure; myocardial infarction; coronary artery disease
Description	The article deals with the pathophysiological basis for the combination of angiotenzin-converting enzyme (ACE) inhibitors and angiotenzin II type 1 receptor blockers (sartans) in the treatment of hypertension, heart failure and conditions after myocardial infarction and in the secondary prevention of coronary artery disease. The risks of combining these substances are discussed, particularly in terms of recent critical literature reviews of this combination, and a very careful consideration of the indications for coadministration of ACE inhibitors and sartans is emphasised.
Related projects:	Early diagnostics and treatment of cardiovascular diseases