Phenotypic Analysis of CD19+ Subsets In Monoclonal Gammopathy Patients

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Authors

KOVÁŘOVÁ Lucie ZARBOCHOVÁ Pavla VARMUŽOVÁ Tamara BUREŠOVÁ Ivana MUTHU RAJA Karthick Raja PENKA Miroslav HÁJEK Roman

Year of publication 2010
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description Our result showed differences in CD19+ subsets when compared peripheral blood of healthy volunteers and monoclonal gammopathy patients as well as in bone marrow of monoclonal gammopathy group. These differences could be a sign of ongoing changes in B cells of monoclonal gammopathy patients. Further analysis will be also focused on changes at DNA level to confirm clonality of selected subpopulations and to find possible myeloma stem cells source.
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