Growth/differentiation factor-15 is an abundant cytokine in human seminal plasma

Warning

This publication doesn't include Faculty of Sports Studies. It includes Faculty of Science. Official publication website can be found on muni.cz.
Authors

SOUČEK Karel SLABÁKOVÁ Eva OVESNÁ Petra MALENOVSKÁ Alice KOZUBÍK Alois HAMPL Aleš

Year of publication 2010
Type Article in Periodical
Magazine / Source Hum. Reprod.
MU Faculty or unit

Faculty of Science

Citation
Field Physiology
Keywords Seminal plasma; Growth/Differentiation Factor 15 (GDF15/MIC1); FOXP3
Description The GDF-15 concentration in seminal plasma ranged from 0.2 to 6.6 ug/ml as determined by ELISA. Western blot analysis revealed that GDF-15 is present in the active form. In vitro cultivation of sperm cells with GDF-15 did not affect their viability or rates of apoptosis; however, it did inhibit proliferation of PBMCs and induce expression of FOXP3 in CD4+CD25+ cells.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.

More info