Fluctuation of the low-spectrum peak frequency and baroreflex sensitivity in cross-spectra of blood pressure and heart rate in young diabetics

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Authors

HONZÍKOVÁ Nataša JAVORKA Michal TONHAJZEROVÁ Ingrid JAVORKA Kamil KRTIČKA Antonín ZÁVODNÁ Eva FIŠER Bohumil

Year of publication 2010
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description Positive correlation was found between the frequency of the spectral peak (f) in cross-spectra of systolic blood pressure and heart rate fluctuations (frequency range between 60 and120 mHz) and baroreflex sensitivity (BRS) in a group of young diabetics and in healthy controls. BRS was not constant during several minutes’ monitoring at rest. We recorded blood pressure and heart rate beat-to-beat by Finapres in 14 type 1 diabetics (age 20-25 years, diabetics duration 10-15 years) and 14 age-matched controls for 42 minutes. Results: The mean slope (+-SD) of regression lines (mHz*mmHg/ms) was 3.99+-3.46 (p<0.05) in diabetics and 2.77+-2.52 (p<0.05) in healthy controls. It is concluded that a positive correlation between the values of BRS and the frequency of the peak (range 60-120 mHz) in the cross-spectra of systolic pressure and heart rate fluctuations during spontaneous variation of BRS at rest exists in both groups, young diabetics and healthy controls.
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