Haplotypes of the IL-1 gene cluster are associated with gastroesophageal reeflux disease and Barrrett´s esophagus in the Czech population

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Authors

HRDLIČKOVÁ Barbara IZAKOVIČOVÁ HOLLÁ Lydie MAREK Filip DOLINA Jiří KALA Zdeněk

Year of publication 2010
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description Gastroesophageal reflux (GERD) is a major public health problem in the Western world that can lead to a number of complications, such as reflux esophagitis, Barretts esophagus, and adenocarcinoma. Although no significant role of single IL-1 variants in reflux disease was found in our study, IL-1 haplotypes may be associated with susceptibility to GERD and Barretts esophagus.
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