grid-CICADA: Efficient Explorer of Conformational Space of Biomolecular Systems

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Authors	ŠTĚPÁN Jakub KULHÁNEK Petr KŘÍŽ Zdeněk KMUNÍČEK Jan KOČA Jaroslav MATYSKA Luděk
Year of publication	2010
Type	Appeared in Conference without Proceedings
MU Faculty or unit	Faculty of Science
Citation
Description	Knowledge of conformational space is essential in assessment of dynamical behaviour of biomolecules, which is important, for example, in drug design and folding studies. Unfortunately, systematic exploration of conformational space is impossible due to its high complexity. To circumvent this problem, we have developed the program CICADA that tries to rationalize the search in such a space. In this work, we will demonstrate utilization of innovated version of CICADA in the grid environment during the study of selected middle size biomolecules.
Related projects:	Proteins in metabolism and interaction of organisms with the environment Biomolecular centre