Non-invasive determination of baroreflex open-loop gain in man
| Authors | |
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| Year of publication | 2010 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | The non-invasive evaluation of open-loop feedback gain (G) of the baroreflex in humans was the aim of the present study. G is the response of blood pressure to the baroreceptor stimulus of 1 mmHg described by the equation: G=Ghr+Gsv+Gtpr (Ghr - gain of heart loop, Gsv - gain of stroke volume loop, Gtpr - gain of total peripheral resistence loop). Gains were calculated in 14 healthy young subjects; these mean values (+-SD) and renges were found:Ghr: 1.11(+-0.69), 0.23-2.5; Gsc: 0.88 (+-0.51), 0.35-2.0; Gtpr: 1.01 (+-0.36), 0.3-1.7; G: 3.008 (+-1.31), 1.13-5.5. It is concluded that baroreflex open-loop gain variability between the subjects is relatively large; the variability of the gain of cardiac loop is bigger than the variability of the gain of the peripheral resistance loop. |
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