Evolution of protein modularity
| Authors | |
|---|---|
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | Current Opinion in Structural Biology |
| MU Faculty or unit | |
| Citation | |
| Field | Genetics and molecular biology |
| Keywords | Protein evolution; modular structure; protein sequence networks in sequence space |
| Description | Proteins in their evolution follow several discrete stages, which is reflected in their modular organization. The sequences of the protein modules are highly variable while their functions and structures are rather conserved. The relatedness of the variable sequences is well represented by the networks in natural sequence space that also suggests evolutionary connections |
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