Revisiting the planarity of nucleic acid bases: Pyramidilization at glycosidic nitrogen in purine bases is modulated by orientation of glycosidic torsion

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Authors	SYCHROVSKÝ Vladimír FOLDÝNOVÁ-TRANTÍRKOVÁ Silvie ŠPAČKOVÁ Naděžda ROBEYNS Koen VAN MEERVELT Luc BLANKENFELDT Wulf VOKÁČOVÁ Zuzana ŠPONER Jiří TRANTÍREK Lukáš
Year of publication	2009
Type	Article in Periodical
Magazine / Source	Nucleic Acids Research
MU Faculty or unit	Faculty of Science
Citation
Field	Biophysics
Keywords	bases of nucleic acids; molecular dynamics; NMR; quantum chemistry
Description	We describe a novel, fundamental property of pyramidilization at the N1/9 sites of purine and pyrimidine bases. The study combines analyses of ultra-highresolution X-ray structures together with quantum chemical calculations, molecular dynamics simulations, and published solution nuclear magnetic resonance data.
Related projects:	Biomolecular centre