Je kombinace inhibitorů ACE a blokátorů receptorů pro angiotenzin II v léčbě kardiovaskulárních onemocnění indikovaná?

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Title in English	Is the combination therapy with ACE inhibitors and angiotensin II type 1 receptor blockers indicated in the treatment of cardiovascular diseases?
Authors	VÍTOVEC Jiří ŠPINAR Jindřich
Year of publication	2009
Type	Article in Periodical
Magazine / Source	časopis Remedia
MU Faculty or unit	Faculty of Medicine
Citation
Field	Cardiovascular diseases incl. cardiosurgery
Keywords	angiotensin-converting enzyme inhibitors; angiotensin II type 1 receptor blockers; hypertension; heart failure; myocardial infarction; coronary artery disease
Description	The article deals with the pathophysiological basis for the combination therapy with ACE inhibitors and angiotensin II type 1 receptor blockers (sartans) in the treatment of hypertension, heart failure, post myocardial infarction condition and in secondary prevention of CAD. In particular, risks posed by this combination therapy that influences angiotensin II formation or action are discussed in the light of clinical trials and clinical practice.
Related projects:	Early diagnostics and treatment of cardiovascular diseases